Cytotoxicity - Wikipedia
Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are toxic metals, toxic chemicals, microbe neurotoxins, radiation particles and even specific neurotransmitters when the system is out of balance.
Cytotoxic: Definition, Agents, Effects, and Precautions - Verywell …
2022年5月24日 · Cytotoxic means that a substance or process can damage cells or cause them to die. "Cyto" means cell and "toxic" means poison. You might hear the word when talking about chemotherapy drugs that kill cancer cells. It can also describe …
What is Cytotoxicity? - News-Medical.net
2021年6月22日 · Whilst toxicity is a more general term for how harmful a substance is to an organism; cytotoxicity is the term for how toxic a substance is to cells. A cytotoxic compound can cause cell damage...
Cytotoxicity Assays: In Vitro Methods to Measure Dead Cells
2019年5月1日 · A frequent use of cells in culture is for a commonly used cytotoxicity assay where cells are exposed to a test compound and after some period of incubation, a marker is measured to reflect the number of viable cells present compared to positive (toxin) and negative (vehicle) control treatments.
Drug toxicity assessment: cell proliferation versus cell death
2022年10月14日 · The development of reliable, accessible, and scalable viability assays based on cell death–associated effects of biomarkers is extremely important for efficient screening of drug toxicity. The 3...
Cytotoxicity - an overview | ScienceDirect Topics
Cytotoxicity can be defined as the adverse effects observed from reactions with structures or crucial processes for cell maintenance such as proliferation, survival, and normal biochemistry and physiology.
An early history of T cell-mediated cytotoxicity - Nature
2018年4月16日 · This Timeline looks back at the past 60 years of fundamental research into the mechanisms of T cell-mediated cytotoxicity, which has culminated in recent interest in the therapeutic manipulation...
T cell-mediated cytotoxicity - Immunobiology - NCBI Bookshelf
Cytotoxic effector proteins that trigger apoptosis are contained in the granules of CD8 cytotoxic T cells. The principal mechanism through which cytotoxic T cells act is by the calcium-dependent release of specialized lytic granules upon recognition of antigen on the surface of a target cell.
Cytotoxicity Definition, Identification, and Cytotoxic Compounds
2019年10月2日 · This book presents important information pertaining to the molecular control of the mechanisms of cytotoxicity and cellular proliferation as they relate to cancer.
Cytotoxicity - an overview | ScienceDirect Topics
Cytotoxicity refers to the ability of immune cells like CD8+ T lymphocytes and NK cells to induce cell death in target cells, often used to assess the effectiveness of immunotherapies in cancer treatment.