Intrahepatic cholangiocarcinoma (small and large duct types)
2021年8月23日 · Intrahepatic cholangiocarcinoma (iCCA) is a malignant intrahepatic epithelial neoplasm with biliary differentiation, arising in the liver periphery / proximal to the left and right hepatic ducts (WHO 2019)
Cholangiocarcinoma - StatPearls - NCBI Bookshelf
2024年5月6日 · Cholangiocarcinoma is an aggressive malignancy of biliary epithelium that may arise anywhere in the biliary tract, from the intrahepatic biliary canaliculi to the terminus where the common bile duct enters the duodenum at the duodenal ampulla.
Cholangiocarcinoma 2020: the next horizon in mechanisms and ... - Nature
2020年6月30日 · Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant tumours that can arise at any point of the biliary tree. Their incidence is increasing globally,...
Cholangiocarcinoma: Classification, Histopathology and Molecular ...
Cholangiocarcinoma (CC) is the second most common tumor of the liver, originating from the biliary system with increasing incidence and mortality worldwide. Several new classifications review the significance of tumor localization, site of origin, proliferation and biomarkers in the intrahepatic, pe ….
Pathological, molecular, and clinical characteristics of ...
This review focuses on the current knowledge of histopathological features, molecular alterations and clinical characteristics of cholangiocarcinoma and its precursor lesions (including biliary intraepithelial neoplasia, intraductal papillary neoplasms of the bile duct, intraductal tubulopapillary neoplasms and hepatobiliary mucinous cystic ...
Pathology of intrahepatic cholangiocarcinoma - PubMed
2016年11月4日 · Intrahepatic cholangiocarcinoma (iCC) is a primary carcinoma of the liver with increasing significance and major pathogenic, clinical and therapeutic challenges. Classically, it arises from malignant transformation of cholangiocytes bordering small portal bile duct (BD) to second-order segmental lar ….
Cholangiocarcinoma - Surgical Pathology Clinics
Cholangiocarcinoma is a heterogenous disease with different definitions, different classification schemes, newly described subtypes, and an evolving knowledge of the molecular basis of this disease. By its most simple definition, cholangiocarcinoma is cancer of the bile ducts.
Cholangiocarcinoma - Nature Reviews Disease Primers
2021年9月9日 · Cholangiocarcinoma (CCA) is a highly lethal adenocarcinoma of the hepatobiliary system, which can be classified as intrahepatic, perihilar and distal. Each anatomic subtype has distinct...
Anatomical, histomorphological and molecular classification of ...
2019年3月18日 · Gross and histological classification of cholangiocarcinoma is based on the anatomy and histology of the biliary tree. Specific precursor lesions with variable rates of malignant progression are recognised.
Epidemiology, risk factors, anatomy, and pathology of ... - UpToDate
2024年1月31日 · Cholangiocarcinomas (bile duct cancers) arise from the epithelial cells of the intrahepatic and extrahepatic bile ducts. Although these cancers are rare in the United States, they are highly lethal because most are locally advanced at presentation.