Serotonin pathway - Wikipedia
Projections into the hippocampus are the most dense in the subiculum, followed by Ammon's horn and the Dentate gyrus. Projections into the VTA modulate firing rate, increasing the rate with lower activity, and depressing it with higher activity.
Serotonergic projections to the orbitofrontal and medial …
In the current study, we focused on three dorsal raphe nucleus (DRN) serotonin projection target areas (the OFC, mPFC, and NAc) and optogenetically stimulated serotonergic axon terminals in these areas during waiting task performance .
A retinoraphe projection regulates serotonergic activity and ...
2017年3月31日 — Simulations of a looming object that mimic an approaching aerial predator can initiate a rapid escape response and retinal projections to the midbrain optic tectum or the mammalian superior ...
A brain-wide functional map of the serotonergic responses ...
2019年1月21日 — Nature Communications - Serotonin is released throughout the brain from diverse projections of neurons in the dorsal raphe nucleus. Here, the authors use optogenetics and fMRI mediated mapping of...
Optogenetic activation of dorsal raphe serotonin neurons ...
2024年5月16日 — The dorsal raphe nucleus (DRN) is a major source of serotonergic projections to brain-wide targets. Here the authors use optogenetics and fMRI to investigate brain-wide...
Serotonergic projections to the orbitofrontal and medial …
2020年11月27日 — Optogenetic activation of serotonergic neurons in the dorsal raphe nucleus (DRN) enhances patience when waiting for future rewards, and this effect is maximized by both high probability and high timing uncertainty of reward. Here, we explored which serotonin projection areas contribute to these effects using optogenetic axon terminal ...
Top-down control of serotonin systems by the prefrontal cortex: a …
2015年7月7日 — The primary serotonergic nuclei that innervate the prefrontal cortex in mammals are the median and dorsal raphe nucleus (MRN, DRN), two brainstem structures that provide the bulk of serotonergic afferents to the forebrain.
Serotonergic versus Nonserotonergic Dorsal Raphe Projection …
2014年9月25日 — Early studies of DRN anatomy led to the view that nearly all of its projection neurons are serotonergic (reviewed in Jacobs and Azmitia, 1992). We have quantitatively compared the composition of the DRN-VTA projections using anterograde, retrograde, and electrophysiological techniques.
Serotonergic - an overview | ScienceDirect Topics
Some important projection sites of the serotonergic system are the hippocampus, amygdala, and cortex. Serotonin has many actions in the body. Its roles include, but are not limited to, integration of cognition, emotion, and motor function.
Serotonergic Projections Govern Postnatal Neuroblast Migration …
2017年5月3日 — Here we identified a serotonergic mechanism that governs migration of postnatally generated neurons in the mouse brain. Serotonergic axons originating from the raphe nuclei exhibit a conspicuous alignment with subventricular zone-derived neuroblasts.
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