Over the last 2 decades, significant progress has been made in our understanding of the genomics, tumor immune microenvironment, and immunogenicity of malignant melanoma. Historically, the prognosis ...

New insights into the brain could pave the way for targeted treatments for anxiety, depression, and other mental health ...

Neuroblastoma (NB), the most prevalent extracranial solid tumor in children, poses a significant therapeutic challenge due to its metastasis and high heterogeneity. A recent study leveraging ...

The researchers took samples from brains of humans and rhesus macaque monkeys, separated individual cells and sequenced their RNA. This shows which genes are active (being expressed) in a particular ...

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So et al. present an optimized protocol for single-nuclei RNA sequencing of adipose tissue in mice, ensuring better RNA quality and nuclei integrity. The authors use this protocol to explore the ...