Renal tubule epithelial cells can be oval to columnar in shape, depending on the segment of the tubule they come from. They are considered to be a marker of tubular damage. When seen with granular ...

Nrp1 can inhibit the aerobic metabolism of distal renal tubular epithelial cells (TECs) by reducing the crotonylation level of Cox4i1, thereby affecting mitochondrial function and aggravating renal ...

EBMD is a disorder of the basal epithelial cells located in the front part of the cornea. These basal cells stick to the second membrane layer, also referred to as Bowman's layer. In EBMD, the basal ...

Depending on the affected organs or tissues, fibrosis can be classified into types such as pulmonary fibrosis, hepatic fibrosis, renal fibrosis, and cardiac fibrosis ... The progression of fibrosis ...

Metformin administration decreased renal expression of necroptosis markers p-RIPK1 (phosphorylated receptor-interacting protein kinase 1) and p-MLKL, along with tubular injury marker KIM-1 (kidney ...

肾脏特异性转录因子Hnf1β (H1)、Emx2 (E)、Pax8 (P) 和Hnf4α (H4) 能够直接重编程或转分化纤维细胞成为诱导的肾小管上皮细胞 ...

On the Origin of Life: How the First Cell Membranes Came to Exist Nov. 13, 2024 — Few questions have captivated humankind more than the origin of life on Earth. How did the first living cells ...

Introduction: Chronic kidney disease (CKD) is a significant healthcare challenge globally and renal proximal tubules (PT) are key targets of injury. Others have shown that patients with CKD have a ...

目前，我们对肾病的发生发展，特别是细胞和分子层面的认识并不明确。因此，许多肾病患者依然会发展为终末期肾脏病（ESRD），其中我们对糖尿病肾病（DKD）的认识也不是特别明确。特别是为什么有些糖尿病患者终身不发生DKD，而有些在确诊糖尿病时，就已经出现了 ...