“Profibrotic monocyte-derived alveolar macrophages are expanded in patients with persistent respiratory symptoms and radiographic abnormalities after COVID-19,” in Nature Immunology. While most people ...

Identifying the underlying causes of prolonged lung inflammation associated with radiographic abnormalities could be key understanding long COVID and other lung conditions, researchers say.

Here the authors show that a population of macrophages, previously described as pro-fibrotic, can be induced through Notch2 blockade and that in a mouse lung injury and fibrosis model this ...

The term “progressive pulmonary fibrosis” or “PPF” is generally used to describe progressive lung fibrosis in an individual with an interstitial lung disease (ILD) other than idiopathic ...

1 State Key Laboratory Cell Differentiation and Regulation, Henan International Joint Laboratory of Pulmonary Fibrosis, Henan Center for Outstanding Overseas Scientists of Organ Fibrosis, College of ...

17 release. The primary goal of the research will be to understand how dysfunctional lung epithelial cells contribute to causing and perpetuating pulmonary fibrosis, according to the release.

The Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center will collaborate with GSK to develop stem cell-based models to better understand pulmonary fibrosis and ...

Idiopathic pulmonary fibrosis (IPF) is characterized by a progressive decline in lung function, worsening quality of life, and high mortality. However, the rate and pattern of progression of IPF ...

In this proof of concept case study we propose multi-gene biomarkers of compounds’ ability to induce lung fibrosis and demonstrate their application in vitro. For deriving these biomarkers we used ...

"I was diagnosed with pulmonary fibrosis, which is the scarring of the lungs, which, when your lungs are scarred, it's harder for the oxygen to go to your blood, so your blood/oxygen levels drop ...