However, less than ten AAV-based therapies have been approved to date. To mitigate the risk of serious side effects and even death, a comprehensive quality control and characterization process is ...

The two organoids emerged as potential adeno-associated virus (AAV) screening models for gene ... for neural progenitor and immature neuronal cells on day 36 and at later culturing stages for ...

Human beings live every day with the understanding of our own mortality, but do animals have any concept of death? It's a question that has long intrigued scientists, fueled by reports of ants ...

CNS-directed AAV gene therapy shows milder immune responses compared to systemic administration, reducing peripheral immune activation and systemic toxicities. Direct CNS delivery can bypass ...

Separating full and empty adeno-associated virus (AAV) capsids during the manufacture of single-gene therapies remains a significant challenge. Ultracentrifugation and anion exchange ...

Throughout history, humans have given a lot of thought to death. We’ve grappled with our mortality, created elaborate burial rituals, and contemplated how best to mourn the loss of a loved one. But ...

Analyzing the purity of adeno-associated virus (AAV)-based gene therapy products requires effective methods for detecting host proteins, DNA, and incomplete viral particles in samples. It is a ...

The Death Stranding ending has a lot to process, with events going to some strange places to reach a conclusion that really needs an explainer for some of its more out there moments - some it ...