When the gene that codes for EGFR has a mutation, it affects the way this protein works, causing cancer. There are many types of EGFR mutations. The EGFR protein lives in the cell membrane with ...

Cheng explains. This becomes even more complicated when disease-causing DNA mutations are introduced into the mix. Some genes can be mutated in many ways to cause the same disease, meaning one ...

Researchers have discovered key mutations in certain cancer cells that make them resistant to WRN inhibitors, a new class of anti-cancer drugs. The yet-to-be-published findings are presented on ...

Oncogenic mutations often involve single nucleotide substitutions at specific hotspots, leading to hyperactive or gain-of-function variants. Tumor suppressor mutations typically involve indels ...

Some research suggests the MTHFR gene mutation, linked to conditions like depression and bipolar disorder, may play a role in ADHD’s onset, too. Treatments like folate supplementation may help.

COVID-19 is evolving and with it the need for new vaccines to protect people against serious illness and death. Australia has detected its first cases of the highly transmissible XEC "recombinant ...

Zhang says this has led some scientists to think that the human sex ratio is not subject to mutation. "But this scenario seems unlikely, because almost all human characteristics are subject to ...

Researchers discovered that mammals - from tigers to humans - have roughly the same number of mutations by the time they die of old age. But short-lived animals tend to burn through their ...