In Posttranslational Modifications of Proteins, Christopher Walsh provides the first comprehensive treatment of the modification processes and their biological consequences. The publication of ...

Arthritis & Rheumatism. 2005;52(12):3829-3838. Study Sheds New Light on This Critical Protein's Involvement in Autoimmunity and Chronic, Corrosive Joint Inflammation Rheumatoid arthritis (RA ...

identifying the importance of posttranslational modifications in mediating the structural diversity of tauopathy strains. Above: Tau filaments decorated with ubiquitin chains (yellow) from ...

Post-translational modification generally refers to the addition of a functional group covalently to a protein as in phosphorylation and neddylation, but also refers to proteolytic processing and ...

Our current efforts are directed toward understanding protein posttranslational modification (PTM) by ubiquitin (Ub) and ubiquitin-like proteins (ISG15 and SUMO) in cellular processes including ...