As noted above, stellate cell activation is the central event in hepatic fibrosis ... interstitial collagenases (MMP-1, -8, -13); (2) gelatinases (MMP-2,-9) and fibroblast activation protein ...
Abstract & Introduction Activated Hepatic Stellate Cells as a Target For Antifibrotic Therapy Current Therapeutic Approaches in Liver Fibrosis Concluding Remarks References Many treatments ...
The HepaStem cells have immunomodulatory properties, similar to other MSCs, and act on the hepatic stellate cells that drive hepatic fibrosis. These immunomodulatory, antifibrotic, and liver ...