Function-engineerable nanoparticles in combination with the advantageous effects of various functional lipid components enable achievement of enhanced blood stability, decreased toxicity and ...

In drug development many applications are found for lipid-based nanoparticles (Lb-NPs ... mechanism and their absorption by the cell’s membrane (endocytosis). Using Lb-NPs as carriers can ...

The lipid nanoparticles that caused an immune response interacted with the cell membrane without disrupting its signaling ...

In this Thought Leader article., Ian Johnston from Cytiva discusses challenges related to process development, scaling technology, regulatory approvals, and GMP guidelines.

In this particular case, messenger ribonucleic acid (mRNA) encapsulated in lipid nanoparticles (LNPs) have been successfully manufactured, distributed and administered to populations throughout ...

Efficient DNA transfection is critical for biological research and new clinical therapies, but the mechanisms responsible for DNA uptake are unknown. Current nonviral transfection methods ...

Penn Engineers have discovered a novel means of directing lipid nanoparticles (LNPs), the revolutionary molecules that ...