Function-engineerable nanoparticles in combination with the advantageous effects of various functional lipid components enable achievement of enhanced blood stability, decreased toxicity and ...

In drug development many applications are found for lipid-based nanoparticles (Lb-NPs ... mechanism and their absorption by the cell’s membrane (endocytosis). Using Lb-NPs as carriers can ...

To address this issue, scientists have developed, and now widely use, the strategy of encapsulating mRNA into lipid nanoparticles ... the filter membrane may foul. Comprehensive analytics form ...

Encapsulated in lipid nanoparticles (LNPs), siRNA can be delivered efficiently to target cells. However, the effectiveness of these therapies hinges on the internal structure of the LNPs ...

The lipid nanoparticles that caused an immune response interacted with the cell membrane without disrupting its signaling ...

In this particular case, messenger ribonucleic acid (mRNA) encapsulated in lipid nanoparticles (LNPs) have been successfully manufactured, distributed and administered to populations throughout ...

The recent success of the mRNA-LNP vaccines fueled biopharma to explore lipid-based nanoparticles for advanced drug delivery. The industry is now poised to exploit the full therapeutic potential ...

More information: Xue, L., et al. Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular ...

Lipidomics is a growing field in the -omics space, bringing together the advances in analytical solutions with bioinformatics to support evolution in the comprehensive study of lipids within ...

WALTHAM, Mass., Oct. 16, 2024 (GLOBE NEWSWIRE) -- ElevateBio, LLC (ElevateBio), a technology-driven company focused on powering the creation of life-transforming genetic medicines, today announced ...