Despite knowing that the active centres of many metalloprotein enzymes are iron porphyrin ... can mimic the activity of various types of cytochrome P450. Can the catalytic activity and reaction ...

Tamoxifen is metabolized to more active metabolites by enzymes encoded by polymorphic genes, including cytochrome P450 2D6 (CYP2D6). Tamoxifen is a substrate for ATP-binding cassette transporter ...

This reaction is due to the efficiency of their body's metabolism of caffeine, which primarily occurs in the liver involving cytochrome P450 (isoenzyme 1A2). In certain individuals, this enzyme is ...